Welcome to Kharelab@Rutgers

The Khare lab seeks to develop new enzymes and proteins using a combination of computational protein design and experimental characterization. Our goal is to develop a quantitative and predictive understanding of enzymatic structures and functions and use this understanding to inform various therapeutic and synthetic applications. Some areas of interest are biodegradation of pollutants, improving cancer chemotherapy, and designing catalytic protein drugs.


Recent News


01/2018 – Joint work with Knapp lab involving modeling of thioether isosteres is accepted for publication in J Mol. Graph. Model. Congratulations, Kristin!

01/2018 – Shreyas Yedahalli (postdoc), Hualin Qiao (grad student) and Joseph Lubin (grad student) join the group. Welcome!

12/2017 – Kristin’s (second in two days!) paper is accepted for publication in JACS! Congratulations!

12/2017 – Kristin’s paper is accepted for publication in Proteins. Congratulations!

10/2017 – We are looking for a postdoctoral fellow to start immediately. See here

10/2017 – Aliza successfully defends her PhD! Congratulations, Dr. Rubenstein! (#3)

10/2017 – Dmitri and Will’s paper (joint work with Fasan lab) is accepted for publication in PNAS. Congratulations!

09/2017 – Welcome to rotation students for Fall’17 Joey Lubin, Skylar Chuang, Hualin Qiao (all CCB) and John Favate (MBS)

09/2017 – Manasi and Lu successfully defend their PhDs! Congratulations Drs. Pethe and Yang! (#s 1 and 2)

08/2017 – Our joint work with Ando lab is accepted for publication in PNAS

08/2017 – Lu’s paper is accepted for publication in ChemBioChem. Congrats!

08/2017 – Our joint work with Fasan lab is published in JACS

08/2017 – Our NSF grant on design of enzyme-based circuits is funded.

07/2017 – Manasi wins Travel Award and Best Poster Prize at the Protein Society Annual Meeting. Congrats!

07/2017 – Our joint work with Baum lab is published (and selected in top 2% of JBC papers in 2017!)

06/2017 – Sagar speaks at the Gordon Conference on Proteins, Holderness, NH

06/2017 – Aliza’s paper is published in PLOS Comp. Biol. Congrats!

05/2017 – Will’s paper is published in Protein Science. Congrats!

04/2017 – Will is awarded Rutgers Presidential Fellowship. Congrats!

03/2017 – Manasi and Brahm’s papers are published. Congrats!